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[223] [224] [225] Extracellular levels of glutamate, the primary excitatory neurotransmitter in the brain, have been shown to increase in the striatum following exposure to amphetamine

Nevertheless, most of these biomarkers are diagnostic, meaning they are elevated by the time the disease is clinically present, thus with scarce predictive capacity

Natural alternatives to GLP-1 drugs Actual prescriptions aside, the GLP-1 craze has elevated the larger conversation around weight management and blood sugar control

The precise mechanism underlying ferroptosis is still unknown, but it is known that altered iron metabolism, glutathione (GSH) depletion, GPX4 inactivation, and increased PUFA peroxidation by ROS play key roles in its onset and progression [80, 81]