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New or worsening headaches are common and can make falling or staying asleep difficult

This makes them more effective than traditional appetite suppressants that rely on stimulatory pathways

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Effective strategies include prioritizing protein intake (0.7 to 1 gram per pound of goal body weight daily), staying well hydrated (64 to 80 ounces of water daily), consuming at least 1,200 to 1,500 calories daily despite reduced appetite, including complex carbohydrates for sustained energy, maintaining regular physical activity even when tired, optimizing sleep quality (7 to 9 hours nightly), checking for and addressing nutrient deficiencies, and using moderate caffeine strategically if needed