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Semaglutide is a synthetic GLP-1 RA (receptor agonist)

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Patients should monitor for signs that might suggest complications, including: Persistent lumps lasting beyond 24-48 hours Increasing size, hardness, or tenderness at the injection site Redness, warmth, or signs of inflammation suggesting possible infection Bruising or bleeding that seems excessive Itching, rash, or hives indicating potential allergic reaction According to the UK Summary of Product Characteristics for Ozempic, injection site reactions are classified as 'uncommon' (may affect up to 1 in 100 people)

Third, if the solution has visible particles or remains cloudy after 15 minutes of gentle mixing at room temperature, do not use it