However, some connections have been found between different molecular classes and clinical features, including eating behavior and obesity
Similarly, hydration also matters: collagen requires water to function, and dehydrated skin shows texture changes more prominently
This timeline is based on stability testing under standard storage conditionstypically room temperature or refrigeration depending on the formulation
Disclosures: Zobair Younossi: Nothing to Disclose, Alexandra Ellis: Stratevi, LLC: Employee, Jackie Lee: Intercept: Employee of Stratevi, LLC, which received funding from Inter, Leona Bessonova: Nothing to Disclose, Radhika Nair: Intercept Pharma: Employee, Sanofi: Employee, Elizabeth Potente: Nothing to Disclose, Robert Gish: please see full disclosures document: Consultant 2354 IMPROVING KNOWLEDGE IN PBC MANAGEMENT BEYOND FIRST-LINE THERAPY: STRUCTURED LEARNING INCREASES COMPETENCE AND CONFIDENCE S Christy Rohani-Montez 1 Marinella Calle 1 Jrn Schattenberg 2 David Jones 3 , 1 Medscape Education Global, 2 University Medical Center Homburg, 3 Newcastle University, UK Background: Up to ~40% of patients with PBC have an inadequate response or poor tolerability to UDCA leading to an increased risk of end-stage liver disease