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While the chemically induced models of PD, MPTP and 6-OHDA, provide valuable insight into the oxidative stress-related mechanisms of dopaminergic neuron loss in vivo , they do not fully recapitulate PD neuropathology with -syn aggregation (Meredith and Rademacher, 2011

Furthermore, we evaluated the relationships between their improvements in HbA1c and the baseline characteristics of the subjects, including their cognitive function and insulin secretory capacity

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