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Further analysis, however, is necessary to determine whether nucleolin may specifically influence the stability or expression of GPx-1

The mechanism is not well established it may relate to individual sensitivity, dehydration coinciding with supplement use, or other unrelated factors

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Staff cited inadequate substance characterization, uncertain product quality, insufficient evidence of effectiveness for ulcerative colitis, sparse human safety data, and unresolved risks such as immunogenicity, aggregation, impurities, and long-term exposure