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Model outputs include costs, life expectancy (measured in years), quality-adjusted life expectancy (measured in quality-adjusted life years [QALYs]), the cumulative incidence of all modeled diabetes complications, and mean hypoglycemia rates in each simulation arm, along with differences in cost, life expectancy and quality-adjusted life expectancy outcomes between simulation arms and the incremental cost-effectiveness ratio (ICER)

The response is still individual, but the dual-incretin design appears to enhance fat loss for many patients

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(2021) The Long-Term Effects of Growth Hormone Replacement on Bone Mineral Density and Trabecular Bone Score: Results of the 10-Year Prospective Follow-up Tan KT, Luo SC, Ho WZ, Lee YH