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however, the Ki-67 index had increased to 70%, indicating a higher proliferative activity ( Figure 5 )

It mainly relies on inflammasome to activate the part of the proteins in the caspase family, causing them to cut Gasdermin D protein, activate Gasdermin D protein, and the activated Gasdermin D protein is translocated to the membrane to form holes

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Measurement of the TNF- and IL-1 by ELISA The TNF- and IL-1 levels in the perihematomal were determined using ELISA kits (USCN Life Science Inc., Wuhan, China) according to the manufacturers instructions