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Sitagliptin was not mutagenic or clastogenic with or without metabolic activation in the Ames bacterial mutagenicity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay

Rotating sites prevents the buildup of thickened skin or fatty lumps, a condition known as lipodystrophy

doi: 10.7150/thno.73896 53 SheltonLMHuysentruytLCSeyfriedTN

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