depression on semaglutide The GLP-1 (#Ozempic) failed to improve mood and executive functioning in this, the first RCT of a GLP-1 for major #depression: Semaglutide and Depression Risk: Clinical

When combined with interventions that support metabolic resilience, cellular maintenance, and behavioral stability, they may contribute to maintaining physiological function over time

Wegovy and Ozempic both contain semaglutide as their active ingredient

A three-year randomized, double-blind, placebo-controlled trial in 818 older adults (aged 50-70 years) with elevated homocysteine levels but normal serum vitamin B 12 levels found that folic acid supplementation (800 g/day) lowered homocysteine levels and improved measures of memory performance (115)

Tail vein blood was collected in K3 EDTA-coated capillary Microvette tubes (Sarstedt)