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Current theories concerning disease pathogenesis include an imbalance between protease and anti-protease activity, induced apoptosis of alveolar cells through deregulation of pathways involved in oxidative stress, chronic inflammation, and aberrant tissue remodeling that lead to the destruction of the extracellular matrix (ECM) in the lung [3, 4]

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In human AD brains, mitochondrial dysfunction correlates with the burden of A and tau

Lifestyle factors: A diet high in sugar, inactivity, poor sleep, and stress can all contribute