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It is one of the causative substances

Semaglutide primarily leads to mild-to-moderate and transient gastrointestinal disturbances like nausea, vomiting, and diarrhea

Interestingly, the insulin/IGF-1 pathway displays an antagonistic pleiotropy with aging, i.e., during development insulin/IGF-1 signaling has fundamental functions in cellular differentiation and the growth of animals, whereas later in the life, it regulates metabolism but its activity clearly accelerates the aging process [1, 2]

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