tirzepatide and being cold Why Am I on Tirzepatide? Causes & Solutions Does Tirzepatide Cause Cold Sensitivity?

Semaglutide is a GLP-1 receptor agonist that works by: Reducing appetite Increasing fullness Slowing gastric emptying Improving insulin sensitivity Brand-name versions include: Ozempic (commonly used off-label for weight loss) Wegovy (FDA-approved specifically for chronic weight management) Semaglutide has one of the largest bodies of clinical evidence in obesity medicine

These providers can rule out other causes (thyroid dysfunction, pregnancy, underlying reproductive conditions) and confirm whether tirzepatide adjustment or dose slowing might help

As such, DPP-4 inhibitors, which reduce the breakdown of native incretins, and GLP-1 receptor-agonists, which mimic native GLP-1, are classes of medications that take advantage of this pathway [95]

Karhausen, J