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Fosgonimeton failed its primary endpoint in three separate clinical trials: ACT-AD (Phase 2, mild-to-moderate Alzheimers disease, June 2022)

Preferred injection sites: Abdomen (2 inches away from navel) Front or outer thigh Back of upper arm Site rotation: Alternate injection sites to prevent tissue irritation, scarring, or lipodystrophy

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1