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[DOI] [PMC free article] [PubMed] [Google Scholar] 241.Zanbili F., Poursattar Marjani A

This recruitment is crucial for efficient mitophagy: depleting all three VDACs impairs Parkins targeting to defective mitochondria and mitochondrial degradation, yet each individual VDAC can redundantly support Parkin recruitment and mitophagy (147)

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Conservative treatments can be thought of as lifestyle changes (better nutrition and more moderate exercise), mechanical (MLD, compression garments and compression pumps), and supplements/medications