MACE 4P: episodio compuesto cardiovascular de 4 puntos, incluyendo adems hospitalizacin por angina inestable
Because Sermorelin stimulates your bodys own growth hormone production, there is a theoretical risk that excessive or prolonged use could lead to symptoms associated with elevated growth hormone levels, such as joint pain, swelling, metabolic changes, or an increased risk of diabetes
Common side effects include nausea, vomiting, and gastrointestinal disturbance
The key milestones include: exenatide approval (2005), liraglutide approval (2010), semaglutide injection approval (2017), oral semaglutide with SNAC approval (2019), orforglipron cryo-EM structure published (2020), orforglipron Phase 2 results in NEJM (2023), orforglipron Phase 3 ATTAIN-1 results in NEJM (2025), and FDA regulatory submission (2025)