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Targeting amino acid metabolism for cancer therapy

These cells detect the presence of nutrients in the intestinal lumen via chemosensory G protein-coupled receptors (GPCRs) and taste receptors , and in response, release hormones that influence digestion , appetite , and glucose metabolism

In the same study, glutamic pyruvate transaminase was five-fold higher in periportal hepatocytes versus centrilobular hepatocytes but increased in both areas of the lobule during a three-day fast