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In this context, the absolute risk reductions afforded by GLP-1 RA therapy become more pronounced, as demonstrated in multiple cardiovascular outcome trials where the benefits were most evident among those with prior disease 4,10,41

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Phase 2 data published in June showed that once-weekly CagriSema led to an average 15.6% bodyweight reduction at week 32 among type 2 diabetes patients living with overweight or obesity

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