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2018;10(6):e2741

The results indicate that pirAEs constitute a clinically severe and potentially fatal category of ICI-related toxicities, most commonly presenting as immune-related pneumonitis, interstitial lung disease, and respiratory failure

Antioxidants such as polyphenols, vitamins, alkaloids, polysaccharides, and active peptides (Figure 1) help to maintain the structure and function of neurons and prolong their healthy state ( FIGURE 1 Polyphenols Polyphenols are the most abundant antioxidant in plants and have an excellent ability to capture oxidative free radicals (Jiang et al., 2016)

Supports Sleep Regulation and Quality DSIP is best known for its involvement in sleep-related signaling