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You might experience constipation due to slower digestion and less food moving through your system

Safety Signals, Side Effects, and Muscle Loss The most discussed retatrutide vs tirzepatide side effects are gastrointestinal

The exact mechanism is unclear, GLP-1s interact with brain pathways involved in appetite and autonomic regulation, and might be changing how you perceive sensations like warmth and cold, potentially making you more sensitive than youd otherwise be

The glucagon receptor activation enhances energy expenditure and promotes fat oxidation, essentially helping the body burn stored fat more efficiently