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bmjmedicine.bmj.com/content/5/1/e0 We used VA data to emulate a target trial

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PACSIN2 encodes a lipid-binding protein that interacts with Rac1, the molecular target of thiopurines ( MOCOS, MAT1A, MAT2A , and TYMS , though not directly involved in thiopurine metabolism, have also been implicated in thiopurine resistance because of their TPMT activity-altering action (Karas-Kuzelicki et al., 2010