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A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome

In studies using perfused pig and rat pancreata, researchers in Denmark and the US described potent insulinotropic (10, 11), and glucagonostatic (12) effects in vitro , while studies in healthy humans revealed that circulating levels of GLP-1 increased after nutrient intake and confirmed GLP-1 to be an incretin hormone in vivo (13)

Environmental Triggers: External factors, such as certain viral infections, may activate the disease, especially in genetically predisposed individuals

doi: 10.1016/j.molmet.2025.102124