glp-1 for psoriasis agonists reduce severity and inflammation | JAMA Dermatology posted on the topic GLP-1RA & Inflammatory Skin Diseases

Interestingly, the sidechains of SLC25A43 residues K226 and R227 appear near R225 and D226 sidechains in SLC25A39, where the positively charged K226 replaces the negative charge of D226 in SLC25A39

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Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study

Importantly, GHK-Cu did not negatively impact cell proliferation or NO secretion in these macrophages, suggesting its protective effects were specific to inflammatory pathways rather than general cytotoxicity [1]