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COPD is a chronic and uncontrolled inflammatory process that is perpetuated by continued exposure to cigarette smoke, oxidative stress, impaire/resolution pathways, and activation of immune cells [22]

Cui S-S, Feng XB, Zhang BH, Xia ZY, Zhan LY (2020) Exendin-4 attenuates pain-induced cognitive impairment by alleviating hippocampal neuroinflammation in a rat model of spinal nerve ligation

Metabolic and epigenetic coordination of T cell and macrophage immunity

Studies have revealed that MSCs secrete several soluble factors that contribute to their immunomodulatory effects and regulate immune cell responses [41, 42]