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The FDA approval of the first oral GLP-1 for weight loss in December 2025-Novo Nordisk's once-daily semaglutide pill-represents a watershed moment for the category [3]

Take it on an empty stomach with no more than 4 oz of water, then no food, drink, or other oral medication for at least 30 minutes

Ozempic is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is used as a once-weekly subcutaneous injection to improve blood glucose control in adults with type 2 diabetes and reduce the risk of major cardiovascular events in patients with established cardiovascular disease, and lower the risk of kidney failure in patients with chronic kidney disease and type 2 diabetes