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The early activation of PI3K strongly enhances the resistance of cortical neurons to hypoxic injury via the activation of downstream targets of the PI3K pathway and the normalization of the levels of PARP activity, ATP, and NAD+

Ciebiera M, Wodarczyk M, Wrzosek M, Mczekalski B, Nowicka G, ukaszuk K, Ciebiera M, Sabuszewska-Jwiak A, Jakiel G

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Research also indicates that extracts of Withania somnifera (1.4 g/kg B.wt.) and Bauhinia purpurea (2.5 mg/kg B.wt.) can stimulate thyroid activity in female mice