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GLP-1s are not currently recommended during breastfeeding

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The reviewed data show that maternal exposure to GLP-1 agonists causes reduced embryonic-fetal survival, increases in major congenital anomalies, reduced fetal weight/growth, retardation of ossification, irregular ossification and skeletal variants in mice, rats and rabbits

Their ability to improve metabolic health, reduce systemic inflammation, and lower surgical complication rates makes them valuable in optimizing patient outcomes