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An additional post-hoc sensitivity analysis was performed by excluding the ITCA 650 trial [9] to investigate both primary and secondary outcomes to validate the robustness of the pooled analysis (Supplementary Appendix D)

This medication is widely used in the treatment of type 2 diabetes mellitus and is also recognized for its ability to support clinically significant weight loss when combined with lifestyle changes

TECAR triggers biological responses, including enhanced blood flow and oxygenation, increased cellular metabolism, improved lymphatic drainage, reduced inflammation, and pain relief

Identity: Confirmed by mass spectrometry and peptide mapping consistent with the C194H312N54O59S2 composition and amylinanalogue sequence