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DOI: 10.1177/1359105308095977 Linardon J, Messer M, Rodgers RF, Fuller-Tyszkiewicz M

For example, in the EMPA-REG OUTCOME trial, patients randomized to receive empagliflozin experienced a significant reduction in cardiovascular death, all-cause mortality, and hospitalization for heart failure compared to placebo despite only modest differences in HbA1c between groups [22]

A study involving healthy individuals found that this hormone not only stimulated insulin release, but also increased insulin-independent glucose disposal

Conclusions Despite being classified as a generally regarded as safe (GRAS) substance, carrageenan consumption appears to cause insulin resistance by inducing subclinical inflammation among overweight individuals, with this effect mediated by pro-inflammatory changes in the gut