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Some patients feel the effect almost immediately after starting the medication, says Jessica Bartfield, M.D., an obesity medicine physician and associate professor at Wake Forest University School of Medicine who specializes in medical weight management

Sexual side effects can occur with either drug

The average age of participants in the original trial was 63, and many were more than a decade past menopause at the time of enrollment

However, many experts are now looking at maintenance protocols or using the time on the drug to build substantial muscle mass and metabolic flexibility so that if you taper off, your body is better equipped to maintain the weight