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In July 2024 , Genentech , a member of the Roche Group announced positive topline results from two arms of an ongoing multi-part Phase I clinical trial for CT-996, an investigational, once-daily, oral small molecule GLP-1 receptor agonist being developed for the treatment of both type 2 diabetes and obesity

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Those who interrupted GLP-1 treatment and subsequently resumed before the end of the three-year trial period experienced less benefit compared to those who stayed on the medication, with longer gaps in treatment corresponding to smaller reductions in cardiovascular risk