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Rybelsus: The Oral GLP-1 Option Rybelsus contains the active ingredient semaglutide in an oral tablet form

Changes in Frequency and Consistency Beyond frank diarrhoea or constipation, many patients notice subtler changes such as altered stool consistency (described using the Bristol Stool Chart, types 1-7), different timing of bowel movements, or fluctuations between loose and formed stools

Reduced intraepidermal nerve fiber density in HIV-associated sensory neuropathy

Mounjaro (tirzepatide) Also a once-weekly injection, but tirzepatide targets both GLP-1 and GIP receptors a dual-action approach that has produced the strongest weight loss results seen in clinical trials to date (2025% average loss at the highest dose)