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Pulm Pharmacol Ther 20:922, PMID: 16458553 Cotgreave IA (1997) N -acetylcysteine: pharmacological considerations and experimental and clinical applications

The receptor target is shared, but the experimental design, the model selection, and the interpretive frame all shift when the ligand is a Trp33-dependent, partial, biased small molecule rather than a peptide

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Rockefeller has an incredibly rich history of research on the endoplasmic reticulum, so we know that when things go wrong in this organelle, many diseases ranging from neurodegeneration to cancer can result, says Birsoy