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Other circadian clock proteins, such as Rev-erb have also been implicated as a mediator of microglial activation and neuroinflammation, where the authors observed a time of day difference in microglial immunoreactivity in the hippocampus (Griffin et al., 2019)

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"We do see some reports of interaction between astaxanthin and blood pressure meds, as well as drugs which regulate blood sugar," says Gasic