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Unlike the majority of transamination reactions, the enzyme catalyzing the formation of saccharopine does not employ pyridoxal phosphate as a cofactor

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These pharmacokinetic characterisation studies established Mod-GRF 1-29 as the short-acting GHRH analogue of choice for research applications requiring pulsatile GH release patterns, and documented its full GHRH-R agonism and cAMP-driven somatotroph activation equivalent to native GHRH