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The next era is not GLP-1 versus surgery. That debate is already outdated

Following renal injury, fibroblasts undergo differentiation into myofibroblasts, marked by the expression of alpha-smooth muscle actin and the development of excessive extracellular matrix proteins

Long-chain fatty acids that are used as energy source, are activated by the palmitoyl-CoA synthetase localized on the outer surface of the outer mitochondrial membrane [27, 28], and converted by CPT-I at the same site [8-10]

Additionally, CuCP molecules can be integrated into a liposomal-based nanosystem to form biocompatible and stable CuCP nanoparticles (CuCP Lipo NPs)