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By inducing ROS accumulation, modulating mitochondrial membrane potential, and activating oxidative stress-related pathways, the nanozyme suppresses tumor proliferation and restores sensitivity to chemotherapeutic agents such as 5-FU [101]

We and others have shown that GLP-1 drugs reduce risks of many substance use and addiction disorders

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In parallel, Glp2r sequences display the most rapid protein sequence evolution, and show greater variability in amino acids at sites involved in ligand interaction, however most were not predicted to have a functional consequence