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Kagara, N., Tanaka, N., Noguchi, S

alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells Richard J Elliott 1 , Marika Szabo, Mark J Wagner, E Helen Kemp, Sheila MacNeil, John W Haycock Use of low-dose naltrexone in the management of chronic pain conditions: A systematic review Elizabeth Hatfield, Kristine Phillips, Sahar Swidan, Lawrence Ashman PMID: 33228882 DOI: 10.1016/j.adaj.2020.08.019 Sr Care Pharm 2019 Jan 1;34(1):43-46

[3] Beyond its direct antimicrobial effects, LL-37 has immunomodulatory functions

These doses are well tolerated and have no meaningful toxicity risk, as excess B12 is excreted in urine rather than accumulating in tissues