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Cell-mediated immunity plays a central role, with nave CD4 + T cells differentiating into effector subsets upon antigen recognition: Th1 cells secrete IFN-, IL-2, and TNF-, inducing MHC class II expression and promoting Fas-mediated apoptosis of thyrocytes

Based on these results, low levels of tryptophan could contribute to anxiety ( They may also increase aggression and impulsiveness in aggressive individuals ( On the other hand, supplementing with tryptophan may promote good social behavior ( Summary Research has shown that low levels of tryptophan may contribute to mood disorders, including depression and anxiety

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