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[1] [2] Short-chain fatty acids (primarily acetic, propionic, and butyric acids), which microganisms form in the intestines, bind to the FFAR2 and FFAR3 receptors on K cells and L cells to stimulate their respective production and secretion of GIP [3] and GLP-1

It's important to note that off-label use is legal and sometimes necessary in medical practice, allowing doctors to adapt treatments to individual patient needs

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Allulose has been shown to stimulate GLP-1 , the same hormone targeted by modern weight loss drugs, while behaving more like fiber than sugar in the body