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If we can make the atrium a less favorable environment for AFib, ablation has a better chance to work. Next Steps: Larger Trials and Broader Applications of GLP1 Therapy While LEAF was a relatively small, singlecenter study, the magnitude of benefit observed has generated interest in larger trials to confirm the findings and determine optimal timing and duration of GLP1 therapy

For UPLC/MS/MS, the sample extracts were reconstituted in acidic or basic LC-compatible solvents