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The KPV fragment retains the anti-inflammatory properties of alpha-MSH but lacks the receptor-binding activity that causes melanocortin side effects such as skin darkening or appetite changes

Immunocytochemistry analysis of THP-1 cells labeling Glutathione peroxidase 1 with Mouse anti-Glutathione peroxidase 1 antibody (EM1901-56) at 1/100 dilution

This pair is the consensus answer because it lifts the bodys own growth hormone rather than replacing it

Because it does not suppress the body's natural hormone production (unlike exogenous hormones), it is considered to have a clean systemic safety profile in the context of the available data