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Abstract Metformin, a cornerstone therapy for type 2 diabetes mellitus, has emerged as a promising cardioprotective agent with effects that extend well beyond glycemic control

A recent and more extensive ( N = 10,690 people with diabetes followed up over 67 years) historical cohort study observed a reduced association between GLP-1RA use compared with non-use for depressive and, more pronouncedly, anxiety disorders incidence, especially in women 32

therefore, the involvement of pathways, such as endothelial NO synthase and antioxidant signaling, is inferred rather than directly demonstrated

Liraglutide 3.0mg (Saxenda) should only continue beyond 12 weeks if you've lost at least 5% of your initial body weight