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Hypoxia Chronic persistent or intermittent hypoxia (IH) triggers ECD leading to both inflammation and oxidative stress [131, 132]

BMC Pregnancy Childbirth 22, 263

Sunflower seeds and pumpkin seeds offer zinc and other minerals that serve as cofactors in glutathione metabolism

During inflammatory processes, triglycerides undergo hydrolysis, forming free fatty acids (FFA) (Zhu et al., 2022), which are toxic to hepatocytes and induce apoptosis through both extrinsic and intrinsic pathways ( (2) Toxic Lipid Metabolites: The metabolism of lipids produces toxic metabolites such as malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), and malondialdehyde-acetaldehyde adducts (MAA), which further damage mitochondria and promote free radical production (Schaffert, 2009)