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However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro

Potential contraindications include: Pregnant or breastfeeding women should not undergo Epithalon therapy, as there is insufficient research to confirm safety for mother and child

The main toxicity provoked is acute liver damage, which is mechanistically provoked by the aberrant adduction of the toxic metabolite N-acetyl p-benzoquinone imine (NAPQI) to cysteinyl residues of key liver proteins [105]

Epigenetic transgenerational inheritance of obesity susceptibility