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Other studies have suggested beneficial effects of L-carnitine supplementation on inflammatory parameters 55 , in the secondary prevention of CVD 54,56 , in diabetes mellitus 57 , on serum lipid profile in hemodialysis patients 58 , for adults with end-stage kidney disease on hemodialysis 59 or for patients in maintenance hemodialysis 60 , though detailed analysis of whether the carnitine was provided in oral vs intravenous supplementation, bypassing the gut microbiota, has not been extensively evaluated