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Dose-response relationships appear to be tissue-specific, with adipose tissue showing high sensitivity while other tissues may require higher concentrations for detectable effects

Key points include: Legal Use : Classified as Research Use Only in the U.S., it cannot be used for human consumption

The progression of disease is slow and symptoms can take a few years to present

239.) Available from: Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Homocysteine, Cleveland Clinic,