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This includes eligibility screening, dose titration, a critical phase in tirzepatide therapy where doses advance from the 2.5 mg starting dose through escalating levels (5 mg, 7.5 mg, 10 mg, and 12.5 mg or 15 mg), and ongoing monitoring of metabolic and clinical outcomes

Industry Growth and Market Dynamics The generics market for GLP-1 receptor agonists has expanded dramatically, following several key medications losing patent protection

For the thigh specifically: 1/2 inch (12.7mm): The most versatile length for thigh injections

Disclosures: Johanna Schaub: Pliant Therapeutics: Employee, Pliant Therapeutics: Stock - publicly traded company, Richard Ahn: Nothing to Disclose, Fawzy Barry: Nothing to Disclose, Dorothea Kent: Nothing to Disclose, Prerna Kotak: Pliant Therapeutics: Stock - publicly traded company, Pliant Therapeutics: Employee, Scott Turner: Nothing to Disclose, Jennifer Lai: Nestle Nutrition Institute: Grant/Research Support, Novo Nordisk: Consultant, Genfit: Consultant, Boehringer Ingelheim: Advisor, Martin Decaris: Nothing to Disclose 2409 GALLBLADDER NEOPLASIA IS ASSOCIATED WITH A HIGHER RISK OF BILIARY NEOPLASIA IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS Mitchell Clayton 1 John Eaton 1 Ross Dierkhising 1 Andrea Gossard 1 Gregory Gores 1 Konstantinos Lazaridis 2 Nicholas LaRusso 1 , 1 Mayo Clinic Rochester, 2 Mayo Clinic Background: Chronic inflammation in those with primary sclerosing cholangitis (PSC) leads to a multifocal field effect, increasing the possibility of synchronous and metachronous neoplasia in the gallbladder (GBN) and biliary tree (BN)