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mansoni and puts forward annual mortality estimates of schistosomiasis in excess of 200,000 in Africa alone
At clinical concentrations, pretomanid does not inhibit major CYP isoenzymes, including CYP1A2, CYP2C8, CYP2C9, CYP2C19 or CYP2D6, and does not induce CYP2C9 or CYP3A4, limiting the potential for DDI trough CYPs
Limited clinical data hinder confident conclusions despite positive findings in animal models
Kefir grains contain up to 61 strains of bacteria and yeasts, making them a very rich and diverse probiotic source, though this diversity may vary
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