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Combined Approaches (Neelakantan et al., 2022): NNMT inhibition with reduced-calorie diet produced dramatic adiposity reduction in DIO mice, normalizing metabolic parameters and establishing a distinct gut microbiome

In preclinical studies published in Endocrinology, researchers found that chronic administration of AOD-9604 reduced body weight and body fat in obese mice while increasing beta-3 adrenergic receptor expression to levels comparable with lean mice

In the United States, the Food and Drug Administration (FDA) has not approved the body protective compound for medical use, meaning it does not meet the agencys safety and efficacy standards

Titilola Falasinnu and Nathan Lelooked at posts on Reddit, a website where people with lupus share their experiences and ask for advice